After working one of the worst mass killings in U.S. history, Scarpetta returns home to Cambridge, Massachusetts. However, she is called to examine the body of a young woman. Physical evidence links the case to a series of uniquely weird homicides in Washington, D.C., where Scarpetta's FBI husband has been deployed to help capture a serial killer dubbed the Capital Murderer. It will require the usual ensemble of characters to find out the truth, including Scarpetta's sidekick Pete Marino, who has undergone a drastic change in his life that places him center stage in a Cambridge investigation that puts everyone at risk.

After working on one of the worst mass killings in US history, Chief Medical Examiner Kay Scarpetta returns home to recover, but an unsettling call drives her straight back to work. The body of a young woman has been discovered inside the sheltered gates of MIT, draped in an unusual cloth and posed in a way that is too deliberate to be the killer's first strike. A preliminary examination reveals that the body is covered in a fine dust that under ultra-violet light fluoresces blood-red, emerald-green and sapphire-blue, and physical evidence links this to another series of disturbing homicides in Washington, DC. As she pieces together the fragments of evidence, Scarpetta discovers that the cases connect, yet also seem to conflict, drawing herself and her team deeper into the dark world of designer drugs, drone technology, organised crime, and shocking corruption at the highest level.

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